WWOX anticorps

N° du produit ABIN5708495

Cet anticorps Lapin Polyclonal détecte spécifiquement WWOX dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour WWOX anticorps (ABIN5708495)

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-WWOX anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids M1-D245 was used as the immunogen for the WWOX antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the WWOX antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the WWOX antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WWOX

Sujet: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

UniProt: Q9NZC7